BRCA1/BRCA2 Testing – Swift Blood Tests

£115.00

4.9/5 from 131+ verified Google reviews

  • Results: ~3 working days
  • Doctor’s report included
  • Convenient home or clinic sampling
  • Free delivery & returns

Biomarkers

This genetic test analyses the BRCA1 and BRCA2 genes for inherited mutations (variants) that increase the risk of certain cancers[1]. It identifies harmful changes, such as deletions, insertions, or substitutions, that may impair the genes’ tumour-suppressing functions[2]. The test may also include assessment of large genomic rearrangements in these genes.

Sample collection: A small blood or saliva sample is taken using a simple kit at home or in one of our UK clinics. Our kit includes everything needed; simply return the sample in the pre-paid envelope. Results include a personalised doctor’s interpretation and genetic counselling recommendations.

Booking details

Age restriction: Adults 18+ only (guardian consent required for minors).

Overview

BRCA1/BRCA2 testing is a genetic screening test that evaluates specific genes for mutations linked to an increased risk of breast, ovarian, and other cancers[1][2]. It helps identify individuals with hereditary breast and ovarian cancer (HBOC) syndrome, allowing for personalised risk management[3]. Your doctor may recommend this test if you have a family history of these cancers or personal risk factors. Swift Blood Tests processes samples rapidly, with results and a doctor’s report typically within a few days.

Key Test Components

BRCA1 Gene Analysis

examines mutations in the BRCA1 gene, which is associated with up to an 87% lifetime risk of breast cancer and 44% risk of ovarian cancer in carriers[1].

BRCA2 Gene Analysis

assesses mutations in the BRCA2 gene, linked to up to a 76% lifetime risk of breast cancer and 17% risk of ovarian cancer, as well as risks for prostate, pancreatic, and male breast cancer[1].

Variant Classification

identifies whether detected changes are pathogenic (harmful), likely pathogenic, benign, or of uncertain significance[2].

Large Rearrangements

detection of deletions or duplications that affect gene function.

Sample Requirements

A blood sample (collected in a purple-top EDTA tube) or saliva sample (using a provided collection tube) is required. No special patient preparation (such as fasting) is needed[4]. Simply drink water and eat normally unless otherwise instructed. Send samples via the next-day laboratory service.

Clinical Uses

Assess cancer risk

Identifying mutations helps estimate lifetime risks for breast, ovarian, prostate, and other cancers[1][3].

Guide prevention strategies

Positive results may lead to enhanced screening (e.g., mammograms, MRI), risk-reducing surgeries (e.g., mastectomy, oophorectomy), or chemoprevention[2].

Inform family planning

Results can guide testing for relatives and reproductive options like preimplantation genetic diagnosis.

Support treatment decisions

For those with cancer, mutations may influence therapies, such as PARP inhibitors for ovarian or breast cancer.

Why You Might Need This Test

You may be advised to take BRCA1/BRCA2 testing if you have any of the following signs or risk factors: - Family history: Multiple relatives with breast, ovarian, prostate, or pancreatic cancer, especially at young ages. - Personal history: Early-onset breast cancer, bilateral breast cancer, or ovarian cancer. - Ethnic background: Higher prevalence in certain groups, such as Ashkenazi Jewish ancestry. - Other indicators: Male breast cancer in the family or known mutations in relatives. For example, a woman with a mother and sister diagnosed with breast cancer may carry a BRCA mutation[3]. Similarly, someone with ovarian cancer might benefit from testing to guide treatment. Your doctor will interpret the results alongside your history and may order additional tests based on the findings.

Can’t Find Your Test?

If you can’t find the test you’re looking for, simply give us a call and our support team will guide you to the right option. We’re here to ensure you get the correct test quickly and confidently.

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FAQs

Frequently Asked Questions

What is BRCA1/BRCA2 Testing?

BRCA1/BRCA2 testing is a genetic analysis that checks for mutations in the BRCA1 and BRCA2 genes, which can increase the risk of breast, ovarian, and other cancers[1]. It provides insight into hereditary cancer risks.

This test is often recommended for those with a strong family history of breast or ovarian cancer, or personal cancer diagnoses, to assess inherited risks and guide prevention[2][3].

No special preparation is usually required[4]. You can eat and drink normally. Genetic counselling is recommended before and after testing.

A small blood sample is taken from a vein in your arm, or a saliva sample is collected using a swab or spit kit. It is quick and routine. You may feel a brief pinch if blood is drawn; afterwards, a bandage is applied. There are minimal risks.

Risks are very low[5]. You might experience slight pain or bruising at the needle site for blood draws, which usually resolves quickly. In rare cases, a small bruise or feeling faint can occur. Saliva collection has no risks.

Results are typically available within 2–3 working days. Swift Blood Tests provides a detailed doctor’s report explaining your results. You will be notified by email or phone as agreed.

Yes. Swift Blood Tests offers a convenient home sample collection kit (saliva or finger-prick blood) with instructions, or you can choose a clinic appointment. Follow the included instructions to collect and return the sample by post.

Results are based on your DNA, so external factors like diet or medications do not typically affect them[6]. However, it’s best to mention any family history or previous genetic tests when discussing results with the doctor.

An abnormal result (pathogenic mutation) indicates increased cancer risk but does not mean you will definitely develop cancer[3]. Your doctor will interpret findings and may recommend enhanced screening or preventive measures.

This test is intended for adults (18+). If testing is needed for a child or teenager, please consult with a paediatric specialist or contact us for guidance.

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